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Adhesion molecules in cancer of the head and neck: role of dysadherin

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Giotakis Ioannis, MD, Professor of Otorhinolaryngology, Athens Medical School, Director of ENT Clinc, Attikon General Hospital, Athens, Greece
2011 Oct-Dec;16(4):609-12.

Adhesion molecules in cancer of the head and neck: role of dysadherin.

Source

ENT Department, University of Athens, Hippokrateion Hospital, Athens, Greece.

Abstract

Dysadherin is a recently discovered cancer-related cell membrane glycoprotein that has an important role in tumor progression and metastasis. We are focusing on the role of dysadherin in E-cadherin downregulation, the different expression patterns of the molecule in cancer of the head and neck and its potential role as a molecular target for future applications in diagnosis, prognosis, and management of the disease.


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