Adhesion molecules in cancer of the head and neck: role of dysadherin
|Giotakis Ioannis, MD, Professor of Otorhinolaryngology, Athens Medical School, Director of ENT Clinc, Attikon General Hospital, Athens, Greece|
Adhesion molecules in cancer of the head and neck: role of dysadherin.
ENT Department, University of Athens, Hippokrateion Hospital, Athens, Greece.
Dysadherin is a recently discovered cancer-related cell membrane glycoprotein that has an important role in tumor progression and metastasis. We are focusing on the role of dysadherin in E-cadherin downregulation, the different expression patterns of the molecule in cancer of the head and neck and its potential role as a molecular target for future applications in diagnosis, prognosis, and management of the disease.